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modified
A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques. The exact definition of a genetically modified organism and what constitutes genetic engineering varies, with the most common being an organism altered in a way that "does not occur naturally by mating and/or natural recombination". A wide variety of organisms have been genetically modified (GM), from animals to plants and microorganisms. Genes have been transferred within the same species, across species (creating transgenic organisms) and even across kingdoms. New genes can be introduced, or endogenous genes can be enhanced, altered or knocked out.
Creating a genetically modified organism is a multi-step process. Genetic engineers must isolate the gene they wish to insert into the host organism and combine it with other genetic elements, including a promoter and terminator region and often a selectable marker. A number of techniques are available for inserting the isolated gene into the host genome. Recent advancements using genome editing techniques, notably CRISPR, have made the production of GMO's much simpler. Herbert Boyer and Stanley Cohen made the first genetically modified organism in 1973, a bacteria resistant to the antibiotic kanamycin. The first genetically modified animal, a mouse, was created in 1974 by Rudolf Jaenisch, and the first plant was produced in 1983. In 1994 the Flavr Savr tomato was released, the first commercialized genetically modified food. The first genetically modified animal to be commercialized was the GloFish (2003) and the first genetically modified animal to be approved for food use was the AquAdvantage salmon in 2015.
Bacteria are the easiest organisms to engineer and have been used for research, food production, industrial protein purification (including drugs), agriculture, and art. There is potential to use them for environmental, purposes or as medicine. Fungi have been engineered with much the same goals. Viruses play an important role as vectors for inserting genetic information into other organisms. This use is especially relevant to human gene therapy. There are proposals to remove the virulent genes from viruses to create vaccines. Plants have been engineered for scientific research, to create new colors in plants, deliver vaccines and to create enhanced crops. Genetically modified crops are publicly the most controversial GMOs. The majority are engineered for herbicide tolerance or insect resistance. Golden rice has been engineered with three genes that increase its nutritional value. Other prospects for GM crops are as bioreactors for the production of biopharmaceuticals, biofuels or medicines.
Animals are generally much harder to transform and the vast majority are still at the research stage. Mammals are the best model organisms for humans, making ones genetically engineered to resemble serious human diseases important to the discovery and development of treatments. Human proteins expressed in mammals are more likely to be similar to their natural counterparts than those expressed in plants or microorganisms. Livestock are modified with the intention of improving economically important traits such as growth-rate, quality of meat, milk composition, disease resistance and survival. Genetically modified fish are used for scientific research, as pets and as a food source. Genetic engineering has been proposed as a way to control mosquitos, a vector for many deadly diseases. Although human gene therapy is still relatively new, it has been used to treat genetic disorders such as severe combined immunodeficiency, and Leber's congenital amaurosis.
Many objections have been raised over the development of GMO's, particularly their commercialization. Many of these involve GM crops and whether food produced from them is safe and what impact growing them will have on the environment. Other concerns are the objectivity and rigor of regulatory authorities, contamination of non-genetically modified food, control of the food supply, patenting of life and the use of intellectual property rights. Although there is a scientific consensus that currently available food derived from GM crops poses no greater risk to human health than conventional food, GM food safety is a leading issue with critics. Gene flow, impact on non-target organisms and escape are the major environmental concerns. Countries have adopted regulatory measures to deal with these concerns. There are differences in the regulation for the release of GMOs between countries, with some of the most marked differences occurring between the US and Europe. Key issues concerning regulators include whether GM food should be labeled and the status of gene edited organisms.
500D Cordura black
T70 black thread
6" mil spec velcro black
2" mil spec webbing black
1" mil spec binding tape green (only on insides)
1" mil spec webbing MOLLE type, black
2" ITW-Nexus tri glides
2" National Molding Lock Monster buckles
1" ITW Nexus Quick Attach Surface Mount (QASM)/Swift Clip...
WTT/WTS
2 G19’s
Gen 3 black
$875
Brand new never fired
Zev pro bbl
Stipling by Coat of Arms
Slide milled and Cerakoted OD green by Coat of Arms
RMR cut w GGP g10 cover plate
Front serations
Atlas trigger kit
Agency magwell
G19X night sights
Gen 4 Battlefield Green
$700
Stippling done by...
I have for sale a Rock island chambered in 9mm I modified to be a budget option for those wanting to test the “2011” platform. Compare it to a staccato p duo, no it’s not as nice in terms of quality control from factory / weight. Shooting wise it’s similar, when I compared it to a friends...
FOR SALE or TRADE ….. Winchester Ranger 20 gauge with 28” barrel and fixed modified choke and Vent Rib . Is in EX condition . Has 2 small wear spots on bluing and a small rub on stock from being bounced around in a gun safe so I am told …. Got this gun on a Trade , and don’t need .
$450.00 out...
New Kabar modified tanto. Bought on a whim and while its really nice I just dont have a use for it as I have too many fixed blades.
Been used to cut paper and that's it. Tossed the box as I got tired of storing it.
Not looking for trades, looking to fund some other projects.
Arsenal imported Saiga SGL-I 21 762x39 Venom Upgraded gas block, barrel cut crowned and threaded at 14.5 with pinned aac 51t break for 16inch overall length with blast out cap. Jmac industries Rear trunion w/ sig 1913 folding stock Alg ultimate lightning bow trigger Ultimac Gas tub rail...
Used. Glock 22 Gen 3. Have owned it since 2010, tons of rounds through it.
Frame work:
Chain link laser stippling with double undercut. Frame Cerakoted, midnight bronze.
Slide: Cerakoted Armor Black with trijicon
HD XR sights.
Buyer responsible for all FFL fees, will meet in the Vancouver...
Please PM questions and comments...thanks
Remington 870 Wingmaster 12 gauge
28" Modified Barrel
3" Magnum
in excellent condition
non vent rib barrel
face to face ... Cash Only
For Shipping: US Postal Money Order + shipping
or
Possible trade for .999 silver bars or 90% silver coins
I have a ruger 10/22 for sale. Only thing still original is the bolt and reciever. Shoots great. Only has about 200 rounds through it. Looking to sell to build a nrl 22 rifle.
Shaw custom bull barrel
Ruger bx trigger
Magpul stock
Bushnell 3-12 scope
Comes with 2 bx 25 mags
3 butler creek mags
1...
I was finally able to buy my dream truck and I may need to sell it now. I will not bore you with the reasons why so let's just get to the reason you're here reading this, the mods list and details.
**If the ad is still up, I still have it**
2016 Dodge Ram 2500 Laramie Limited Edition with the...
I have an extra AK, Century Arms M70AB2 underfolder , modified with Definitive Arms AR adapter . I have all the original parts for the underfolder stock.
Three 30 round magazines- one Tapco, two Magpul.
Tapco trigger group.
Ammo- 680 rounds of 7.62x39 , some Wolf, some Golden Tiger, some...
https://www.msn.com/en-us/news/crime/criminal-case-dropped-against-florida-teen-who-fatally-shot-pal-while-simulating-rap-video/ar-BB1bE1VO?li=BBnbcA1
Hmmmm........seems the shooter was guilty by being negligent to me......
I have two barrels for the 1100 Remington shotgun for sale. Improved and Modified choke, plain barrels, 26 and 28 inches. both 2 3/4 chambers Some scratches but very usable. $125.00 each or will trade for an 1100 smoothbore slug barrel with sights.