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folding
Protein folding is the physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner. It is the physical process by which a polypeptide folds into its characteristic and functional three-dimensional structure from random coil.
Each protein exists as an unfolded polypeptide or random coil when translated from a sequence of mRNA to a linear chain of amino acids. This polypeptide lacks any stable (long-lasting) three-dimensional structure (the left hand side of the first figure). As the polypeptide chain is being synthesized by a ribosome, the linear chain begins to fold into its three-dimensional structure. Folding begins to occur even during translation of the polypeptide chain. Amino acids interact with each other to produce a well-defined three-dimensional structure, the folded protein (the right hand side of the figure), known as the native state. The resulting three-dimensional structure is determined by the amino acid sequence or primary structure (Anfinsen's dogma).The correct three-dimensional structure is essential to function, although some parts of functional proteins may remain unfolded, so that protein dynamics is important. Failure to fold into native structure generally produces inactive proteins, but in some instances misfolded proteins have modified or toxic functionality. Several neurodegenerative and other diseases are believed to result from the accumulation of amyloid fibrils formed by misfolded proteins. Many allergies are caused by incorrect folding of some proteins, because the immune system does not produce antibodies for certain protein structures.Denaturation of proteins is a process of transition from the folded to the unfolded state. It happens in cooking, in burns, in proteinopathies, and in other contexts.
The duration of the folding process varies dramatically depending on the protein of interest. When studied outside the cell, the slowest folding proteins require many minutes or hours to fold primarily due to proline isomerization, and must pass through a number of intermediate states, like checkpoints, before the process is complete. On the other hand, very small single-domain proteins with lengths of up to a hundred amino acids typically fold in a single step. Time scales of milliseconds are the norm and the very fastest known protein folding reactions are complete within a few microseconds.
Up for sale, Southwest, Washington, Vancouver area, Clark County area. Local pick up, cash deal.
4, Camillus folding knifes. Liner lock. Flipper. Steel liners. Nitride coated.
New, never used.
Got 5 of these in a trade deal years ago, I think they retailed for $30 bucks apiece. I used one of...
Ruger Mini 14 Ranch .223 with Butler Creek Folding Stock. Factory 5 rd, 20 rd, two 30 rd mags. for 700.00 firm. Had this since the '90s. Have not used it for over 20 years, so it's time for me to let it go. No box, No old wood stock. No trades. Cash only. I prefer to do the transfer at FFL in...
Didn’t end up using it.
Used like new condition
$200 cash no trades at this time.
Please be aware if you put this on a non SBR’d gun you and your dogs will not be safe from big brother.
Just got one for a friend’s SBR build. Didn’t feel like the shipping was too long. Well worth it, and a great price!
https://www.opticsplanet.com/sig-sauer-mcx-mpx-telescoping-and-folding-stock-black-stkxfoldteleblk.html
Ideally a Midwest industries Alpha, Jmac customs or similar. Would also consider an SB tactical.
Have cash, ammo or other trades. Thanks for any leads.
Lightly used Sig folding stock knuckle to allow AR stocks to be used on the MPX, MCX, or other firearm with a 1913 rail in back by attaching to the picatinny rail and accepting an AR buffer tube. PayPal F&F or Venmo. Will meet in Albany or ship for another $5.
I've got 3 x Law Tactical AR Folding Stock Adapter Gen 3-M in black that I'm looking to sell. Units are brand new, unused, never mounted, and come complete with all original packaging.
There is nothing wrong with these. With the assault weapons ban going into effect I got overly ambitious with...
https://www.opticsplanet.com/sig-sauer-mcx-mpx-telescoping-and-folding-stock-black-stkxfoldteleblk.html
Thought this was a great deal considering what I’ve seen people asking for these around the web, including this forum.
$185 w/ Free Shipping at the time of this post.
I post the thread on reddit first, not stealing pics, so that why i have the time stamp paper in the pic
Mounted and lightly used Ukrainian kpyk folding stock in black, showing wearing from installation and folding 500 plus shipping Sold
Troy ak railed piston tube, installed never fired. 100...
The Combat Exchange side folding SKS stock. Again, had some issues finding this model online. It looks like they stopped being made many years ago. It includes a top pic rail and screws, as well as a heat shield. $100:
Next is a Butler Creek Mini 14 stainless side folding stock. It's for the 5.56 variant, mine is a post-2006, but from what I can tell all years should match up correctly, as well as the mini-30 should fit. Includes the heat shield. I had a hard time finding these online so $100: