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Protein folding is the physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner. It is the physical process by which a polypeptide folds into its characteristic and functional three-dimensional structure from random coil.
Each protein exists as an unfolded polypeptide or random coil when translated from a sequence of mRNA to a linear chain of amino acids. This polypeptide lacks any stable (long-lasting) three-dimensional structure (the left hand side of the first figure). As the polypeptide chain is being synthesized by a ribosome, the linear chain begins to fold into its three-dimensional structure. Folding begins to occur even during translation of the polypeptide chain. Amino acids interact with each other to produce a well-defined three-dimensional structure, the folded protein (the right hand side of the figure), known as the native state. The resulting three-dimensional structure is determined by the amino acid sequence or primary structure (Anfinsen's dogma).The correct three-dimensional structure is essential to function, although some parts of functional proteins may remain unfolded, so that protein dynamics is important. Failure to fold into native structure generally produces inactive proteins, but in some instances misfolded proteins have modified or toxic functionality. Several neurodegenerative and other diseases are believed to result from the accumulation of amyloid fibrils formed by misfolded proteins. Many allergies are caused by incorrect folding of some proteins, because the immune system does not produce antibodies for certain protein structures.Denaturation of proteins is a process of transition from the folded to the unfolded state. It happens in cooking, in burns, in proteinopathies, and in other contexts.
The duration of the folding process varies dramatically depending on the protein of interest. When studied outside the cell, the slowest folding proteins require many minutes or hours to fold primarily due to proline isomerization, and must pass through a number of intermediate states, like checkpoints, before the process is complete. On the other hand, very small single-domain proteins with lengths of up to a hundred amino acids typically fold in a single step. Time scales of milliseconds are the norm and the very fastest known protein folding reactions are complete within a few microseconds.
SB tac folding adapter non buffer Ak style. New no box. I just bought this from another member and it just showed up today But won’t work on the rifle I wanted to put it on without more modifications that I’m willing to make. Just looking to recoup my money.
Perfect condition, this is an all-factory gun from Ruger.
Called the ITAC, it’s a Talo exclusive and comes with an ATI folding and adjustable stock.
Rarely shot, I’d have to say under 300 rounds. Maybe well under.
-Includes Primary Arms MD10 Red dot optic, mounted on Ruger...
3" 12 gauge 18" Rifle Sight Barrel with ATI AR Style Collapsible Folding Stock.
Original Factory Laminated Stock set with Limbsaver Recoil Pad included.
New 12 gauge Shellholder sling also goes with the gun. IC smoothbore.
I have fired only 30 rounds through this gun since it was new.
Got this late last year. POLYMER VERSION.
I had it on a 556 AR converted CMMG .22lr. Gently used with rim fire….
Not a scratch on it and includes lower receiver AR buffer replacement that is new in package.
If you don’t want the AR adapter ….say $170 The pic rail was made in-house by...
Interesting design. Now way in hades I would pay $1800 for it personally. This may have been posted already but I didn't see a thread on it. Kind of like an improved keltec folder. Perhaps with so many ppl suddenly selling off their PCCs and braces they may turn to this instead I dunno.
Selling my JLG/Eagle Arms folding single shot shotgun in 12ga. Fun gun, just needing space in the safe
Im in Eugene, but would drive to Portland for an added $20.
With all the M114 stuff going on, its on you to call the gunstore of choice to ensure they are taking transfers.
All barrels come with a collar adaptor from Spikes Tactical so you can use your drop in .22 conversion kit just by switching out the chamber adaptor with the collar. These collars will work with CMMG and other Ciener type AR15 conversion Kits. Please note these can be a little finicky about...
New, never used folding brace that I took off my MPX and have had sitting in a cabinet for several months. No use to me, maybe it is to someone else. No idea how this intersects with the DOJ's forthcoming rule. Consult your own lawyer before putting it on any firearm, etc. etc.
Shotgun Folding and Extending Stock, Mos/Rem/Win, new condition, never installed. $60 in Eugene
Similar to this one, but not exact match,
For sale is an used, in nice condition, Gearhead works folding arm adaptor with the tailhook mod1 metal brace included. Locks up tight, very solid setup.
GearHead Works MP5,SP5,AP5 folding arm adaptor with TailHook mod1 brace, built in buffer, sling loop and QD mount.
Originally manufactured by Side Project, LLC in 2016, Reptilia is bringing the design back to life as part of a merger with the Side Project team.
The LINK allows seamless attachment of the Magpul Zhukov folding stock to any CZ Scorpion EVO3 S1 firearm (Magpul Zhukov stock included).