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folding
Protein folding is the physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner. It is the physical process by which a polypeptide folds into its characteristic and functional three-dimensional structure from random coil.
Each protein exists as an unfolded polypeptide or random coil when translated from a sequence of mRNA to a linear chain of amino acids. This polypeptide lacks any stable (long-lasting) three-dimensional structure (the left hand side of the first figure). As the polypeptide chain is being synthesized by a ribosome, the linear chain begins to fold into its three-dimensional structure. Folding begins to occur even during translation of the polypeptide chain. Amino acids interact with each other to produce a well-defined three-dimensional structure, the folded protein (the right hand side of the figure), known as the native state. The resulting three-dimensional structure is determined by the amino acid sequence or primary structure (Anfinsen's dogma).The correct three-dimensional structure is essential to function, although some parts of functional proteins may remain unfolded, so that protein dynamics is important. Failure to fold into native structure generally produces inactive proteins, but in some instances misfolded proteins have modified or toxic functionality. Several neurodegenerative and other diseases are believed to result from the accumulation of amyloid fibrils formed by misfolded proteins. Many allergies are caused by incorrect folding of some proteins, because the immune system does not produce antibodies for certain protein structures.Denaturation of proteins is a process of transition from the folded to the unfolded state. It happens in cooking, in burns, in proteinopathies, and in other contexts.
The duration of the folding process varies dramatically depending on the protein of interest. When studied outside the cell, the slowest folding proteins require many minutes or hours to fold primarily due to proline isomerization, and must pass through a number of intermediate states, like checkpoints, before the process is complete. On the other hand, very small single-domain proteins with lengths of up to a hundred amino acids typically fold in a single step. Time scales of milliseconds are the norm and the very fastest known protein folding reactions are complete within a few microseconds.
Brand new KAC 600m rear sight
This sight is still in sealed blister pack.
I take PayPal friends and family/Venmo
Shipping OK, S/H free
No trade requests please.
No separate part sales please
No face-to-face sales requests please
I’m looking to buy a Kriss vector in
( 9mm carbine ) not the pistol with the folding stock not the AR collapsible stock also id rather buy it used as to keep my cost down but if it’s under the retail price that would be great.any extras are a plus.
I may be open to a vector 9 mm pistol for the...
Classic Army brand (airsoft) folding stock used in good condition. I only used the adapter with an SB tactical SBT brace. Fit good with my GSG 522pk and SB brace didn't have to do any mod
2 new GSG mags
$60
Does not come with the SB brace
https://www.sb-tactical.com/product/sbt/
Meet near SE...
Never even had a chance to fire it
Brand new in the box
CZ cleaning kit
Timmy trigger
Two 20 round mags
V6 compensator
HBI extended charging handlHBI selector switches
26" barrel
Will include factory trigger
I do have some 30 round mags available to be sold separately
For sale is a JMAC CUSTOMS 8-Inch Raised Skeleton Stock with JMac 1913 Folding Mech in black. Lightly used.
$180 $140
Cash only, not interested in trades at this time. This is a local sale only, and due to medical issues I can't travel very far from home, so we'd have to meet in Clatskanie...
Great condition. It has been painted once. Still functions perfectly.
Shipped for ten more bucks (it costs about $13 for low level certified USPS)
John @ 503-858-7339
Howdy,
For sale are (2) Sig MCX/MPX folding 1913/Pic Rail extension/buffer tube adapter.
Sig website for reference
$60 for the one with buffer tube and castle nut. Note the buffer tube was cut down a bit, for a tighter/secure fit in the adapter.
$50 for the one without.
Thanks for...
Have a spare telefolder stock for the MCX that I no longer need. Will fit any firearm with a picatinny stock attachment. Great condition.
Willing to ship or meet in Albany. Cash, Paypal F&F, Venmo, or Zelle. Not looking for any trades right now.
This is a used, but in very good condition item, and includes both the stock and brace options. Currently the stock is installed, but you get the brace with the sale.
I had this on a M92 PAP as a brace for a long time, then had the gun registered as an SBR and replaced the brace with a stock...
Description says it all. Lightly used, perhaps <500 rounds. Ended up never really folding my gun. I have a much more robust tool that didn't origionally come with it. The origional instal tool was designed to bend when it was fully tight but this tool will not bend so you can really tighten it...
Finally getting around to listing these.
(5) Vz-58 30rd mags. These are all NOS steel mags from Apex. 7.62x39 of course.
(1) Czech Vz-58 folding stock with mounting hardware. You can find the stock alone cheaper online but without the mounting hardware.
$220 for everything.
Prefer to meet in...
This is a new in bag Lage Left Folding Stock with Picatinny Rail Adapter.
This is the 8 3/4" length I believe. It is 8 3/4 from the end of the butt pad to where the stock meets the Pic adapter.
I bought two of these, but I only ended up using one of them, so I think it is time to make some...
Bought it, test fitted it and then decided to go in a different direction. Comes in the padded cardboard box from Sig. $150 and it's yours. Not really looking for trades. MAYBE 300 Blackout ammo.