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One thing to consider is that some manufacturers may have access to powder that you dont. I use H110 or Winchester 296 - the same powder different branding. Unless I can find a posted load I am very reluctant to exceed the cartridge loads I find in the books. Over the years the loads have become more conservative and are a bit more mild. I have load books that go back 50 years and they reflect this - the question becomes how close is the powder to what it was 50 years ago - I dont know. Another consideration is the availability of chronographs that were scare in the past. I have to believe we know more about are rounds today than they did back then. I shoot a model 28 highway patrolman - so its plenty strong I just dont feel the need to push it hard.