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Makes since but what I disliked about the 22/45 was the angle of the grip not so much the handles, if I would have bought the 22/45 I would have gotten the RP one and put on different panels anyway. All I'm saying is go to the store, try out a bunch of different pistols and find the one that feels the best to you. I held the Ruger, Browning, Beretta, and Walther and my top choices were the Ruger mk3 and Buck Mark, they both fit me and my wife great.That's why I recommended the 22/45 RP. RP standard for Removable Panels. They take modified 1911 grip panels, so you can go thin, thick, wood, plastic, metal, rubber.