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ap5-p
AP5 (also known as APV, (2R)-amino-5-phosphonovaleric acid, or (2R)-amino-5-phosphonopentanoate) is a chemical compound used as a biochemical tool to study various cellular processes. It is a selective NMDA receptor antagonist that competitively inhibits the ligand (glutamate) binding site of NMDA receptors. AP5 blocks NMDA receptors in micromolar concentrations (~50 μM).
AP5 blocks the cellular analog of classical conditioning in the sea slug Aplysia californica, and has similar effects on Aplysia long-term potentiation (LTP), since NMDA receptors are required for both. It is sometimes used in conjunction with the calcium chelator BAPTA to determine whether NMDARs are required for a particular cellular process. AP5/APV has also been used to study NMDAR-dependent LTP in the mammalian hippocampus.In general, AP5 is very fast-acting within in vitro preparations, and can block NMDA receptor action at a reasonably small concentration. The active isomer of AP5 is considered to be the D configuration, although many preparations are available as a racemic mixture of D- and L-isomers. It is useful to isolate the action of other glutamate receptors in the brain, i.e., AMPA and kainate receptors.
AP5 can block the conversion of a silent synapse to an active one, since this conversion is NMDA receptor-dependent.
SPF
Condition - Unifired, Excellent
MKE AP5-P with SB side folding brace
Inlcudes a case, 7 MKE mags, 1 Magpul D60 mag, end cap with sling swivel (not pictured)
$1,450 for everything in the picture.
Transfer paid by buyer, @ your choice of FFL in or around Portland metro area.
Very good condition and runs great. I got a full sized AP5 too so I decided to just keep one. Comes with one MKE 30 round mag and two 20 round KCI mags. Meet at local FFL for transfer.
Like new, hardly fired (two magazines total) MKE AP5-P made in Turkey using HK licensed tooling. Very well assembled with excellent finish. Cocking tube is straight as are the sights. Includes one 30 round steel MKE magazine and original plastic case.
Free shipping to your FFL!
For sale is my like new, MKE AP5-P. Includes SB folding brace (retail cost $250) original box with 2 factory mags, factory mount for red dot and sling.
A really fun gun to shoot, just have to fund other projects. Gun only has 100 rounds through it.
$1500
Will consider trades for IWI Tavor...
For trade is my brand new, unfired MKE AP5-P. Will come with SB folding brace, original box and 2 factory mags.
Looking to trade for IWI Tavor, Sig MCX, Bren, Daniel Defense uppers, LPVOs. Let me know what you have.
Feel free to PM here or preferably text me at
(360) 980-5418