Hook's Drug Stores was an Indianapolis, Indiana-based drug store chain which was founded in 1900 by John A. Hook. The chain flourished throughout central Indiana for most of the 20th-century.
Hook's did business under its own banner, the SupeRX Drug Stores banner outside its core market, and the Brooks Pharmacy banner after acquiring the New England pharmacy chain. The entire company was eventually purchased by fellow Midwestern drugstore chain Revco.
Most former Hook's locations that are still open operate as CVS, which bought out Revco in the late 1990s and rebranded their stores as CVS. The Brooks Pharmacy stores were divested by Revco after the purchase; most of them operate as Rite Aid stores.

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