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spot
SpoT is a bacterial protein that hydrolizes alarmones, (p)ppGpp, in the bacterial stringent response. Its hydrolase activity is Mn2+-dependent with a conserved His-Asp (HD) motif. In E. coli, SpoT protein consists of 693 amino acids. SpoT belongs to the RSH protein family.
It is bifunctional, has both hydrolase and synthase activities. When relA is deleted, E. coli still can produce (p)ppGpp by SpoT.
SpoT can sense many sources of nutrient stress other than amino acid starvation and to respond by limiting hydrolase. The acyl carrier protein (ACP) binds to the TGS domain of SpoT; this binding is probably influenced by the ratio of unacylated ACP to acylated ACP in the cell. Fatty acid starvation leads to a shift in the balance of the two SpoT activities in favor of synthesis. Phosphate starvation is sensed by SpoT hydrolase to elevate (p)ppGpp, which induces IraP, a RssB antiadaptor that antagonizes RssB activation of RpoS turnover, thereby inducing RpoS.
Hey all,
I just finally moved out of washington county to Florence. Unfortunately that lost me access to the tillamook forest and its lanes, however its for the better for me and my wife.
I am going to be a member of the gunclub down here but there are a couple of "restrictions" no steel on...
I hate videos like this but I do believe it's important to view them for lessons learned and to be aware of just how violent the criminal element can be. It's pretty gory at the end so be aware if you don't want to see a lot of blood.
It's pretty messed up as the bad guy pops the guy at the...
22.56 grams Oregon Placer gold smelted button tested to 22k or (.916) purity from acid test (Below spot price!!!)
Spot price as of today is $1349.16
Will sell for $1200.00 obo
smelted down to 4 nuggets equaling 22.45 grams of tested to .916 purity or 22k
Gold prices are going up so I'm going to...
Selling some of my hobby gold that I've found here in Oregon 15.5 grams fluxed and smelted down to 12.349 grams of tested to .916 purity or 22k that's as good as I can get it with my furnace and Flux. Gold prices are going up so I'm going to list a few buttons for anyone interested in having...
I’m looking for a spot to take my son fishing. Bass or bluegill would be great. Preferably shore fishing, but renting a canoe is feasible too. Thank you in advance.
I was going to use it for a dedicated .22 upper or just build a super lightweight upper with it but i am done with projects. This would be good for someone building a super budget lw truck build. one of the sight channel blades broke and was tig welded back on. The weld is ugly but was the only...
My current 20 year old Oakleys are still hanging in there, although the foam gasket is kinda giving out, but $10 shipped seems like a pretty good deal...
Hi there,
I'm new to Northwest Firearms, and while I used to go out target practicing with friends near Olympia, WA, I still haven't found a convenient spot to go near Portland. I was going to just go drive around east of gresham and east of Oxbow park and scope out gravel pits I can see on a...
A friend of mine asked me if I knew anything about this. It was given to him by a family member, but he doesn’t have any use for it. He’s looking to sell it, so he was wondering what it’s worth. Anyone here have any idea?
For sale is one (1) Spot Hogg Fast Eddie/Fast Eddie XL 5-Pin Sight. This is for the sight housing ONLY. It is a Right Hand sight housing. It does include the 3rd axis bracket/screws, so this should mount to any Fast Eddie/Fast Eddie XL set-up you already have. It also includes three (3) MRT...
For sale is one (1) Spot Hogg Fast Eddie 5-Pin archery sight. This is a Right Hand sight. It is in Perfect condition and has only been to an indoor range. Comes with Nock On edition Extended Sight Tapes. None of the sight tapes have been used or applied to the sight. If it came in the retail...
For sale is one (1) Spot Hogg Fast Eddie Double Pin archery sight. It is in Perfect condition and has only been to an indoor range. Comes with Nock On edition Extended Sight Tapes. None of the sight tapes have been used or applied to the sight. If it came in the retail box...it's included here...