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If you are looking at the specs side-by-side the differences are very small ... I assume you can fire them both through the same barrel.

The .44 magnum specifications: and the .41 magnum:

Bullet diameter .429 in (10.9 mm) ________________ .410 in (10.4 mm)
Neck diameter .457 in (11.6 mm) ________________ .434 in (11.0 mm)
Base diameter .457 in (11.6 mm) _______________ .434 in (11.0 mm)
Rim diameter .514 in (13.1 mm) _______________ .492 in (12.5 mm)
Rim thickness .060 in (1.5 mm) ________________ .060 in (1.5 mm)
Case length 1.285 in (32.6 mm) _______________ 1.290 in (32.85 mm)
Overall length 1.61 in (41 mm) ________________ 1.590 in (40.4 mm)

From Wikipedia.org
 
You can NOT shoot .41s out of a .44 barrel!
I got a super early production DE44 with a secondary magazine that is marked "41", it doesn't work very well compared to the real-deal 44 one.
The real DEs made to shot 41 Magnum are super rare...

It CAN however be converted to '50AE easily, but expensive, by buying a new barrel and magazine for it. The bolt is the same on both.
 
You can NOT shoot .41s out of a .44 barrel!
I got a super early production DE44 with a secondary magazine that is marked "41", it doesn't work very well compared to the real-deal 44 one.
The real DEs made to shot 41 Magnum are super rare...
It CAN however be converted to '50AE easily, but expensive, by buying a new barrel and magazine for it. The bolt is the same on both.

After reading some internet forums, I am now convinced you cannot shoot the .41 Mag through a .44 Mag barrel.
 
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