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Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals (including humans) as a neurotransmitter. Its name is derived from its chemical structure: it is an ester of acetic acid and choline. Parts in the body that use or are affected by acetylcholine are referred to as cholinergic. Substances that increase or decrease the overall activity of the cholinergic system are called cholinergics and anticholinergics, respectively.
Acetylcholine is the neurotransmitter used at the neuromuscular junction—in other words, it is the chemical that motor neurons of the nervous system release in order to activate muscles. This property means that drugs that affect cholinergic systems can have very dangerous effects ranging from paralysis to convulsions. Acetylcholine is also a neurotransmitter in the autonomic nervous system, both as an internal transmitter for the sympathetic nervous system and as the final product released by the parasympathetic nervous system. Acetylcholine is the primary neurotransmitter of the parasympathetic nervous system.In the brain, acetylcholine functions as a neurotransmitter and as a neuromodulator. The brain contains a number of cholinergic areas, each with distinct functions; such as playing an important role in arousal, attention, memory and motivation.Acetylcholine has also been traced in cells of non-neural origins and microbes. Recently, enzymes related to its synthesis, degradation and cellular uptake have been traced back to early origins of unicellular eukaryotes. The protist pathogen Acanthamoeba spp. has shown the presence of ACh, which provides growth and proliferative signals via a membrane located M1-muscarinic receptor homolog.Partly because of its muscle-activating function, but also because of its functions in the autonomic nervous system and brain, many important drugs exert their effects by altering cholinergic transmission. Numerous venoms and toxins produced by plants, animals, and bacteria, as well as chemical nerve agents such as Sarin, cause harm by inactivating or hyperactivating muscles through their influences on the neuromuscular junction. Drugs that act on muscarinic acetylcholine receptors, such as atropine, can be poisonous in large quantities, but in smaller doses they are commonly used to treat certain heart conditions and eye problems. Scopolamine, which acts mainly on muscarinic receptors in the brain, can cause delirium, hallucinations, and amnesia. The addictive qualities of nicotine are derived from its effects on nicotinic acetylcholine receptors in the brain.
BCM square/star forge mark upper receiver, BCM .625 gas block and CMT DRT 10.5 handguard. Selling these together for $220.00
Upper and gas block have no rounds on them, upper was fit to a couple lowers and gas block was test fit to barrel. Second owner of the handguard. Great condition, has a...
Bought it from someone who claimed to have been issued and deployed with this helmet so pretty cool.
If you plan on wearing it you may want new padding.
New Revision Advanced Combat Helmet, complete with pads, chinstrap, and Ocp Multicam Cover. Helmet is rated for IIIA Ballistic protection and is made for the Army by Revision. This ACH is a little lighter and thinner than most but carries the same protection rating. Size Medium asking for $180...
USGI Army Advanced Combat Helmet(ACH). Manufactured for the Army by Gentex in Size Medium the helmet is made of Kevlar with a IIIA protection rating. Current issue to all ground forces. Helmet shell has no damage and is in great condition and comes complete with USGI Issue Multicam OCP helmet...
For sale is an ACH size MD from Specialty Defense Systems. This helmet, cover, straps and pads are all in excellent condition. $150 shipping on your dime. F2F anywhere in Clark County along hwy 14 corridor.
U.S. military surplus Advanced Combat Helmet (ACH) Size large, manufactured by Gentex. This is used, but in very good condition. These kevlar helmets offer protection against handgun rounds. Let me know if you have questions.