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The U.S.–UAE 123 Agreement for Peaceful Civilian Nuclear Energy Cooperation is a 123 Agreement on peaceful nuclear cooperation between the United States of America and the United Arab Emirates, which entered into force on 17 December 2009 and enables the UAE to receive nuclear know-how, materials and equipment from the U.S. As part of the agreement, the UAE committed to forgo domestic uranium enrichment and reprocessing of spent fuel, as well as sign the International Atomic Energy Agency's Additional Protocol, which institutes a more stringent inspections regime on the UAE's nuclear activities. The UAE's agreement to forgo enrichment and reprocessing has become known as the nonproliferation "gold standard" for nuclear cooperation agreements, because the signatory renounces the sensitive technology and capabilities that can also be used to produce a nuclear weapon.

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