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Agents of S.H.I.E.L.D. is an American television series created for ABC by Joss Whedon, Jed Whedon, and Maurissa Tancharoen, based on the Marvel Comics organization S.H.I.E.L.D. (Strategic Homeland Intervention, Enforcement and Logistics Division), a fictional peacekeeping and spy agency in a world of superheroes. It is set in the Marvel Cinematic Universe (MCU), sharing continuity with the feature and short films of the franchise.The series stars Clark Gregg, reprising his role of Phil Coulson from the films, as well as Ming-Na Wen, Brett Dalton, Chloe Bennet, Iain De Caestecker, and Elizabeth Henstridge. Nick Blood and Adrianne Palicki joined the cast for the second and third seasons, while Henry Simmons and Luke Mitchell had recurring roles in the second season before being promoted to the main cast for the third. John Hannah, who recurred in the third season, joined the main cast in the fourth, while Natalia Cordova-Buckley, who recurred in both the third and fourth seasons, was promoted to the main cast for the series' fifth season. Jeff Ward was promoted to the main cast for the sixth season after recurring in the fifth. Additionally, several other characters from Marvel Cinematic Universe films and Marvel One-Shots also appear throughout the series, along with other characters based on various Marvel Comics properties. Several characters from the series also appear in the supplemental digital series Marvel's Agents of S.H.I.E.L.D.: Slingshot.
This list includes the series' main cast, all guest stars deemed to have had recurring roles throughout the series, and any other guest who is otherwise notable.

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