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That's why I carry 9mm. 32+ rounds on my person everyday. Haha. You make good points though. There is no guarantee.In my own experience, there is no perfect bullet or perfect caliber, bullets do strange things when hitting, having to deal with clothing, angles, distance, speed, all that, and we want a sure stop each hit, the odds ain't in our favor, so we also need to look at capasity, it will likely take more then one shot to stop a threat. Combined, ballistics gives you an approximate idea of what to expect in a perfect situation, but, it also can show you the weakness, taken with experience or a calibers known performance history, we can make a decision on which might be the best for us to carry. And finally, having made that choice, we need to test the ammo in our carry pistols to determine if it shoots well enough to serve as a carry load! I'm not going to try and sell anyone anything, everyone has their own standard of performance they judge acceptable, and that's just fine. Me, I want the most power and velocity I can get, I want to drive that bullet through heavy clothing, windshields, car doors, and such, and I want it to drive deep enough to reach vitals no matter the angle the tango is at, outside the big magnums I found the Big 10 ticks all the boxes, so that's what I carry. Problem is, good quality carry ammo is rare, if you can even find it, so your almost forced to hand load your own. I have no issue doing that, but I know others don't agree it's a good idea! With the Big 10, pushing a 200 grain soft point at just over 1300 FPS is about as good as it gets!
A 180 gr hollow point smokin along at nearly 1400 FPS is a seriously powerful load, and leaves little doubt of it's stopping power in flesh!