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My favorite powder for .45 ACP in an autoloader so far for moderate target loads and light recoil is Accurate #2. It can be kind of dirty in .45ACP revolvers, but works well in my CZ97 for light target or heavier bowling pin loads, with bullets from 200 grains up to 250. I've heard good things about Bullseye for these loadings, got a can of that to try out.
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This is interesting. I love the Accurate powder line because it seems so clean (I try not to post my love too much lest people get the wrong idea). I have in my powder cabinet a half bottle of Bullseye (many years old) and 3.5 bottles of accurate #2 (less than a year old due to frequent replacement). The reason is that in my SP101 revolver, Bullseye gums it up so that after about 100 rds the cyclinder locks up till I clean it -- Literally won't work. When I had the gun new I thought it was broken. With A#2, I can shoot a couple hundred rounds and it's still ready to go for more just like when it's sparkly clean.
Is there a reason a powder might be clean in a narrow case like a .38 but dirty in a .45 and why a different powder would be the opposite? I'm not disputing your experience -- it's just so opposite of mine I wonder if there is something going on in relatively wider cases vs. narrower cases.