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If camping, the biggest problem mammal could be a bear. I used to hunt bear way back and can report that a Colt Peace Maker 45 will do the job at close range. But if the potential adversary is anyting like a bear, I would want 357/41/44 mag. Saw one bear shot with a 30-06 ahead of the hounds. He ran another 100 yards or so before he dropped. When we gutted him out, it was a blown apart heart we found. He ran 100 yards with NO BLOOD PRESSURE. The ancient worship of bears for their strength is based upon fact. Smaller calibers will indeed just make them mad.
Black bear maybe. But I would never want to go toe to toe with a big brown or heaven forbid, a grizzly with a .45 Colt (or anything, for that matter)