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Note, I don't recommend the .243 Win unless you have the shooting skills to put the bullet exactly where it needs to go, if not, your making the animal suffer while you take follow up shots, or some one else has to finish it off!
I've seen people make bad shots with magnums (myself included). Bullet placement is always an issue, with any cartridge. My maternal grandfather took more elk when he was young than most hunters on this board have seen, and he did it with a .30-30.
There are limits with any cartridge, and the suggestions I have seen so far are good, as long as the pros and cons are understood.