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On August 1, 1966, after stabbing his mother and his wife to death the night before, Charles Whitman, a former Marine, took rifles and other weapons to the observation deck atop the Main Building tower at the University of Texas at Austin, then opened fire indiscriminately on people on the surrounding campus and streets. Over the next 96 minutes he shot and killed 14 more people (including an unborn baby) and injured 31 others. One final victim died in 2001 from the lingering effects of his wounds. The incident ended when a policeman and a civilian reached Whitman and shot him dead. The attack was the deadliest mass shooting by a lone gunman in U.S. history until it was surpassed 18 years later by the San Ysidro McDonald's massacre.
It has been suggested that Whitman's violent impulses, with which he had been struggling for several years, were caused by a tumor found in the white matter above his amygdala upon autopsy.

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